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New research: A transient transcriptional activation governs implantating embryo morphogenesis

Posted on 2024/07/01

DGCR8 acts as a transcriptional repressor by binding to target nascent RNAs and sequestering FLII. During implantation, ERK-induced FLII phosphorylation enables dissociation of the DGCR8/FLII complex and formation of the FLII/JUN complex, transiently activating cell migration genes to promote morphogenesis and establish poised pluripotency in implanting embryos. This research is published on Molecular Cell.

New research: Capturing totipotency in human cells through spliceosomal repression

Posted on 2024/06/05

Two states of totipotency could be captured using splicing inhibition as a handle to reprogram human pluripotent stem cells. The first transient represents a distinct ZGA-like state that could subsequently transition into stable, totipotent blastomere-like cells that express pre-ZGA-specific genes. This research is published on Cell.

Congratulation to three new doctors!

Posted on 2024/05/23

The journey of earning a Ph.D. is filled with rigorous challenges, and we congratulation to Chunhui, Siwen and Ruijie for their successful finishing their journey!

Campus Open Day 2024

Posted on 2024/04/13

The laboratory instructors provide science popularization to mid school students on the Campus Open Day 2024!

Spring outing 2024: Universal Studios Beijing

Posted on 2024/04/08

Universal Studios!

Autumn outing 2023: Datong, Shanxi

Posted on 2023/10/22

On a two-day journey, we visited Yungang Grottoes, Huayan Temple, and Hengshan Mountain in Datong, Shanxi.

Happy birthday to Dr.Peng Du 2023!

Posted on 2023/08/06

Summary outing 2023: Picking cherries and flower beds

Posted on 2023/06/02

Picking cherries and visiting flower beds in the suburbs of Beijing.

Doctor, doctor, doctor and doctor!

Posted on 2023/05/22

Today we congratulate to the four new Doctors, Dr.Shiyu Li, Dr.Xuehui Lyu, Dr.Ye Qi and Dr.Yingzi Cui. They all have published good papers and become postdoctoral fellows in our lab. Congratulations!

Spring outing 2023: Olympic Forest Park

Posted on 2023/03/17

Spring is a good season for admiring flowers.

The Lantern Festival 2023

Posted on 2023/02/05

On the Lantern Festival 2023, we had delicious dinner and home-party!

Bing Peng Received her Ph.D.!

Posted on 2022/11/20

Congratulations To Bing Peng for her finishing the training! She will be postdoctoral fellow and continue to research on interesting projects.

Happy birthday to Dr.Peng Du 2022!

Posted on 2022/08/06

Min Yang Received Her Ph.D!

Posted on 2022/05/23

Congratulations to Min Yang! She built the bioinformatics analysis platform in our in the early stages of the laboratory. Thanks for her contribution!

Our Website Launched!

Posted on 2022/05/26

Our Website Is Launched On 2022/5/26. Welcome To Enjoy The RNA And Stem Cell World!

Hui Shen Received Her Ph.D!

Posted on 2021/12/05

She is the first one who finished Ph.D. training in our lab! She will be a postdoctoral fellow and work with us in the following several years. Congratulations!

Autumn outing 2021: Jinhai Lake, Pinggu, Beijing

Posted on 2021/10/15

Two days of sightseeing, Jinhai Lake and homestays.